Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A Tumor-Agnostic NTRK (TRK) Inhibitor.

Huang, Franklin W; Feng, Felix Y.

Cell ; 177(1): 8, 2019 03 21.

Artigo em Inglês | MEDLINE | ID: mdl-30901551

2.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Ghandi, Mahmoud; Huang, Franklin W; Jané-Valbuena, Judit; Kryukov, Gregory V; Lo, Christopher C; McDonald, E Robert; Barretina, Jordi; Gelfand, Ellen T; Bielski, Craig M; Li, Haoxin; Hu, Kevin; Andreev-Drakhlin, Alexander Y; Kim, Jaegil; Hess, Julian M; Haas, Brian J; Aguet, François; Weir, Barbara A; Rothberg, Michael V; Paolella, Brenton R; Lawrence, Michael S; Akbani, Rehan; Lu, Yiling; Tiv, Hong L; Gokhale, Prafulla C; de Weck, Antoine; Mansour, Ali Amin; Oh, Coyin; Shih, Juliann; Hadi, Kevin; Rosen, Yanay; Bistline, Jonathan; Venkatesan, Kavitha; Reddy, Anupama; Sonkin, Dmitriy; Liu, Manway; Lehar, Joseph; Korn, Joshua M; Porter, Dale A; Jones, Michael D; Golji, Javad; Caponigro, Giordano; Taylor, Jordan E; Dunning, Caitlin M; Creech, Amanda L; Warren, Allison C; McFarland, James M; Zamanighomi, Mahdi; Kauffmann, Audrey; Stransky, Nicolas; Imielinski, Marcin.

Nature ; 569(7757): 503-508, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-31068700

3.

Club-like cells in proliferative inflammatory atrophy of the prostate.

Huang, Franklin W; Song, Hanbing; Weinstein, Hannah Nw; Xie, Jamie; Cooperberg, Matthew R; Hicks, Jessica; Mummert, Luke; De Marzo, Angelo M; Sfanos, Karen S.

J Pathol ; 261(1): 85-95, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37550827

4.

Transcriptomic profiling and genomic rearrangement landscape of Nigerian prostate cancer.

Mavura, Yusuph; Song, Hanbing; Xie, Jamie; Tamayo, Pablo; Mohammed, Abdullahi; Lawal, Ahmad T; Bello, Ahmad; Ibrahim, Sani; Faruk, Mohammed; Huang, Franklin W.

Prostate ; 83(5): 395-402, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36598071

5.

Cancer Demographics and Time-to-Care in Belize.

Wong, Wayne; Dickerson, James C; Valtis, Yannis K; Habet, Marta; Bernard, Margaret; Kelly, Lorna; Lattin, John; Garrity, Philip; Sood, Rupali; Ohanian, Alec; Chege, Maryanne W; Bhatt, Ami S; Huang, Franklin W; Yacab, Ramon.

Oncologist ; 28(6): e350-e358, 2023 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-36928719

6.

Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.

Stover, Elizabeth H; Oh, Coyin; Keskula, Paula; Choudhury, Atish D; Tseng, Yuen-Yi; Adalsteinsson, Viktor A; Lohr, Jens G; Thorner, Aaron R; Ducar, Matthew; Kryukov, Gregory V; Ha, Gavin; Rosenberg, Mara; Freeman, Samuel S; Zhang, Zhenwei; Wu, Xiaoyun; Van Allen, Eliezer M; Takeda, David Y; Loda, Massimo; Wu, Chin-Lee; Taplin, Mary-Ellen; Garraway, Levi A; Boehm, Jesse S; Huang, Franklin W.

Prostate ; 82(5): 584-597, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35084050

7.

Assessing and Addressing the Need for Cancer Patient Education in a Resource-Limited Setting in Haiti.

Schleimer, Lauren E; Desameau, Peter-Gens; Damuse, Ruth; Olsen, Maia; Manzo, Veronica; Cardenas, Carlos; Mehrtash, Hedieh; Krakauer, Eric L; Masamba, Leo; Wang, Catharine; Bhatt, Ami S; Shulman, Lawrence N; Huang, Franklin W.

Oncologist ; 25(12): 1039-1046, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32335989

8.

DMSO Enhances TGF-ß Activity by Recruiting the Type II TGF-ß Receptor From Intracellular Vesicles to the Plasma Membrane.

Huang, Shuan Shian; Chen, Chun-Lin; Huang, Franklin W; Hou, Wei-Hsien; Huang, Jung San.

J Cell Biochem ; 117(7): 1568-79, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-26587792

9.

Ethanol Enhances TGF-ß Activity by Recruiting TGF-ß Receptors From Intracellular Vesicles/Lipid Rafts/Caveolae to Non-Lipid Raft Microdomains.

Huang, Shuan Shian; Chen, Chun-Lin; Huang, Franklin W; Johnson, Frank E; Huang, Jung San.

J Cell Biochem ; 117(4): 860-71, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26419316

10.

Global Precision Oncology: A Call to Action on Expanding Access to Targeted Cancer Therapies.

Bharadwaj, Maheetha; Vallurupalli, Mounica; Huang, Franklin W.

Oncologist ; 26(5): 353-355, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33539588

11.

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

Babitt, Jodie L; Huang, Franklin W; Wrighting, Diedra M; Xia, Yin; Sidis, Yisrael; Samad, Tarek A; Campagna, Jason A; Chung, Raymond T; Schneyer, Alan L; Woolf, Clifford J; Andrews, Nancy C; Lin, Herbert Y.

Nat Genet ; 38(5): 531-9, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16604073

12.

Racial Disparities in Low-Risk Prostate Cancer-Reply.

Mahal, Brandon A; Huang, Franklin W.

JAMA ; 321(17): 1727-1728, 2019 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-31063570

13.

Randomized Phase II Study Evaluating the Addition of Pembrolizumab to Radium-223 in Metastatic Castration-resistant Prostate Cancer.

Choudhury, Atish D; Kwak, Lucia; Cheung, Alexander; Allaire, Kathryn M; Marquez, Jaqueline; Yang, David D; Tripathi, Abhishek; Kilar, Jacqueline M; Flynn, Meredith; Maynard, Brianna; Reichel, Rebecca; Pace, Amanda F; Chen, Brandon K; Van Allen, Eliezer M; Kilbridge, Kerry; Wei, Xiao X; McGregor, Bradley A; Pomerantz, Mark M; Bhatt, Rupal S; Sweeney, Christopher J; Bubley, Glenn J; Jacene, Heather A; Taplin, Mary-Ellen; Huang, Franklin W; Harshman, Lauren C; Fong, Lawrence.

Cancer Immunol Res ; : OF1-OF15, 2024 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-38552171

14.

Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis.

Chen, Wenjie; Huang, Franklin W; de Renshaw, Tomasa Barrientos; Andrews, Nancy C.

Blood ; 117(23): 6319-25, 2011 Jun 09.

Artigo em Inglês | MEDLINE | ID: mdl-21493799

15.

Prostate Cancer-Specific Mortality Across Gleason Scores in Black vs Nonblack Men.

Mahal, Brandon A; Berman, Rebecca A; Taplin, Mary-Ellen; Huang, Franklin W.

JAMA ; 320(23): 2479-2481, 2018 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-30561471

16.

Understanding inequities in precision oncology diagnostics.

Dutta, Ritika; Vallurupalli, Mounica; McVeigh, Quinn; Huang, Franklin W; Rebbeck, Timothy R.

Nat Cancer ; 4(6): 787-794, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37248397

17.

Racial disparity in the genomics of precision oncology of prostate cancer.

Le, Tu; Rojas, Pilar Soto; Fakunle, Mary; Huang, Franklin W.

Cancer Rep (Hoboken) ; 6 Suppl 1: e1867, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37565547

18.

RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4.

Weinstein, Hannah N W; Hu, Kevin; Fish, Lisa; Chen, Yih-An; Allegakoen, Paul; Hui, Keliana S F; Pham, Julia H; Baco, Maria B; Song, Hanbing; Giacomelli, Andrew O; Vazquez, Francisca; Ghandi, Mahmoud; Goodarzi, Hani; Huang, Franklin W.

bioRxiv ; 2023 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-38106152

19.

Profiling the Somatic Mutational Landscape of Breast Tumors from Hispanic/Latina Women Reveals Conserved and Unique Characteristics.

Ding, Yuan Chun; Song, Hanbing; Adamson, Aaron W; Schmolze, Daniel; Hu, Donglei; Huntsman, Scott; Steele, Linda; Patrick, Carmina S; Tao, Shu; Hernandez, Natalie; Adams, Charleen D; Fejerman, Laura; Gardner, Kevin; Nápoles, Anna María; Pérez-Stable, Eliseo J; Weitzel, Jeffrey N; Bengtsson, Henrik; Huang, Franklin W; Neuhausen, Susan L; Ziv, Elad.

Cancer Res ; 83(15): 2600-2613, 2023 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-37145128

20.

Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.

Song, Hanbing; Bucher, Simon; Rosenberg, Katherine; Tsui, Margaret; Burhan, Deviana; Hoffman, Daniel; Cho, Soo-Jin; Rangaswami, Arun; Breese, Marcus; Leung, Stanley; Ventura, María V Pons; Sweet-Cordero, E Alejandro; Huang, Franklin W; Nijagal, Amar; Wang, Bruce.

Nat Commun ; 13(1): 4878, 2022 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-36008377

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